http://aces.nmsu.edu/ces/yard/2001/021001.html ,
Many pruning sealer compounds are black and contain asphalt. This black material absorbs our New Mexico sunlight and becomes quite hot. The heat can kill the tender cells that the tree produces to close the pruning wound and in that manner delays wound closure and compartmentalization.
Lighter-colored materials do less damage, but any containing a petroleum-based solvent can damage newly developing wound closure cells.Scientific research has shown that the pruning sealer is not necessary. Much more important is proper pruning technique. Knowledge of tree anatomy and physiology allows us to prune a tree and allow the tree to use its protective mechanisms to protect itself.
It is also wise to minimize pruning in landscape trees by training a tree when it is young. Cutting small branches when the tree is young precludes the necessity to cut larger branches later. The large wounds produced by removing large branches create greater difficulties for the tree.