We had a family of rock squirrels in the yard one year, and they stripped every single apple long before they were even close to ripe. I bought a Havaheart trap, and though it took awhile (I'd catch one every few days) I eventually got them all, and dropped each one off in the desert on my way to work. Haven't seen one in the neighborhood since.
I tried a similar approach with pack rats, which seem to be born pregnant and deliver a new litter every other day. They chew holes through everything, eat the bark off my citrus trees, and strip insulation from car wiring. They carry off anything they can lift, and add it to their nests. They also are the favored host for kissing bugs--a type of nasty, blood-sucking parasite named for their habit of biting people on the lips as they sleep. This bug spreads Chagas' disease in Mexico, and now it's starting to appear in Arizona as well. So, living in harmony with the pack rats was not an option.
I had been driving them two miles away to release in the closest bit of natural desert, until on #12 I thought, "I'm trapping two rats per day. Each of these little bundles of joy costs me 20 minutes and the gas for a four-mile round trip. I can't afford to run a rat taxi service." So, I informed #12, "Sorry, little guy, but you're getting a much quicker trip."
I keep a Sharpie handy to make tally marks on the trap. After about 40 rats, things tapered off to where I quit catching them, so I stopped setting the trap and we enjoyed a rat-free winter. A few weeks ago, I started seeing them again. Not as bad as last year, but #45 recently caught the Humane Express to rat heaven, and I'm guessing it will be another busy summer.