when in cup stage, water control gets little touchy. if you water too much, they will die. if you don't, they will die. i use 50/50 perlite/soil. that mix hold water for months under the humidity dome even with daily airing between 30min-few hours. towards the spring when the cup is almost dry, i would very lightly water the soil. i don't mist them. when mist, it's due to the fact that top of the soil is dry.
with 80/20 mix, more than likely your mix will dry up faster. but i wouldn't water unless the cup is definitely lighter and it requires watering. no set schedule. only water as needed.