The moisture holding ability of the Perlite is dependent on particle size. Some bags of Perlite are quite coarse. Some have a lot fines, almost dust. The finer particles hold considerably more moisture. Some of my cuttings, in Perlite/Vermculite mix, never need re-watering, but most get watered every 2 or three weeks. Moistgure is maintained by having water at the bottom of the packing crates, below the screen, to provide continual humidity and the tops open just enough to keep the air fresh. If you limit moisture loss, you need to input less moisture, as well.